Closed‑loop propofol: what’s the target

Ran a sim last week with a prototype closed‑loop propofol controller; in most published systems, which EEG‑derived index range (think BIS) do they auto‑hold to maintain adequate hypnosis under GA? I’m sketching an implementation plan for a limited OR pilot next quarter and want to sanity‑check the target before we lock in protocols.

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OR pilot next quarter and want to sanity‑check the target I’d lock it at BIS 50 with a ±5 deadband (45–55); if EMG spikes or big stimulation hit, let it relax toward 40–60 rather than chasing noise — are you planning prop‑only or prop–remi?

My take: I’d lean toward the simplest next step and see if it changes anything this week — if not, you’ve got a clear case to escalate. What would block you from trying that?

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